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Optimizing Performance
Optimize the Compressibility Compensation Setting
5 Starting with a compressibility setting of 10 × 10
-6
/bar increase the value in
steps of 10. Re-zero the integrator as required. The compressibility
compensation setting that generates the smallest pressure ripple is the
optimum value for your solvent composition.
Table 6 Solvent Compressibility
Solvent (pure) Compressibility (10
-6
/bar)
Acetone 126
Acetonitrile 115
Benzene 95
Carbon tetrachloride 110
Chloroform 100
Cyclohexane 118
Ethanol 114
Ethyl acetate 104
Heptane 120
Hexane 150
Isobutanol 100
Isopropanol 100
Methanol 120
1-Propanol 100
Toluene 87
Water 46